Except for cleaning battery terminals (loosen, remove cables, clean, replace, retighten) or changing batteries I do not turn off the main disconnects to either the house or chassis battery banks.
One exception was my first Winter of ownership I stored the coach in a local building, not plugged in, for several months. I did turn off the main disconnects during that storage period. I went to the storage building at least once every month whereby I turned on the disconnects, started and ran the generator for an hour or so, then turned off the main disconnects again.
While home in the Summer the coach is plugged into 30 amp power when parked in my driveway. The main disconnects are always on. When parked in "my spot" in Yuma the past two Winters the coach was plugged into 50 amp power and the main disconnects are always on.