It sounds like you are going to have to get a good shop involved in your problem, and yes they may be related. If the transmission computer sees excess vehicle speed or excessive RPMs, it will not allow you to shift gears and the it will just flash the key pad and sound an alarm. So if the transmission computer is seeing the same signal that your speedometer is, it is doing what it is programed to do. Therefore, you will need to tie into the data link to determine what is going on, and that will require a shop with the ability to read the data stream.
Gerald