We have been on narrower and curvier roads with our RV while towing. US-22 from Hebo to Valley Junction is plenty wide (just looked on Google Earth satellite view) and has about 1 to 1 1/2 feet of pavement outside the solid white side-stripes. After Valley Junction the road gets wider with maybe 3 to 4 feet of pavement outside the solid white side-stripes. It looks every bit as good (or better) than the McKenzie Highway (126) from Eugene to where it connects with US-20.
If you want to be daring, then try 227 from Canyonville to Trail. We did that one too... from Trail to Canyonville though.