Steve-
I noticed wear on the inside of my Explorer's front tires, and it turned out the front end simply needed alignment.
However, I was suspicious how it may have gotten that way in the first place, aside from normal road hazard effects, and further research led me to a couple of things.
One is that if there is any height difference in hitch hookup points between toad and coach, that can cause unusual toad tire wear; if the toad is low the coach tends to unweight the toad's front end by pulling ever so slightly upward, effectively changing its wheel alignment parameters. If the toad is high (like ours was), the coach tends to pull down and load the toad's front end more than designed, undetectably splaying its tires, and making the toad's set alignment ineffective. Actually, our hitch didn't appear radically off level, so it doesn't take much - a couple inches can make a difference. Roadmaster in Vancouver graciously helped us move the hitch to a more horizontal configuration.
Secondly, as Ed alluded to, when you turn the coach the toad is forced to follow, and especially during turn initiation, the tires scrub a mite. This is eminently true when you make a turn from a dead stop. Picture in your mind a hard right turn onto a cross street after stopping at an intersection. The coach rolls forward, but not straight forward, as you turn the steering wheel right; the toad isn't rolling much at all yet. The coach tailswing actually is forcing the toad hard to its left even though the toad's wheels point straight ahead. You can now imagine a good deal of toad tire scrubbing going on before the coach is rolling straight again with the toad dutifully behind. As Gerald points out, his high mileage comes from the straight freeway driving predominant in his travels - relatively few scrubbing opportunities compared to some of us.
If you make a conscious effort to not make sharp turns from dead stops, that will help a lot; just make sure coach and toad are both rolling forward before initiating a turn, so the hitch is pulling, rather than prying sideways so much with tailswing. And have your toad's alignment checked more often when it's towed a lot; that same tailswing effect can obviously strain a front end and throw things off quicker than normal.
-Joel