Well said, Ed. Get into 6th and stay at the lowest speed that will not cause a shift. I used to go 55-57 everywhere thinking it saved fuel, but realized I never was out of 5th gear there, and the coach wasn't a car. That speed might have worked in our old 454 chev gas coach, but the Allison and diesel engine are different. Nowdays I hit 63 to get into 6th then let it back off to 60; 57 may be the shift point, but get too close to it and she'll shift down at the slightest notion.
Cruise control helps a lot where it can be used, as its electronics provide a steadier foot than humans do, esp. on long flat bumpy roads, eg. California. And tail winds vs. headwinds play a larger part in fuel numbers than many realize.
As to the Howe's product, Gerald is right - its best use is as an anti-gel when the coach is operated in or stored in cold weather. Most diesel already has anti-gel in it, so the next best use for Howe's may only be anti-algae, and I use Power Service's BioKleen additive for that.
Joel