Richard,
Yes that is the tire (295/80/22.5 XZA 2) that I would run, however you need to make the decision about what tire is best for you. I would also recommend that you should run 120 PSI in the tires until you weigh the coach to determine the correct pressure
I am a fulltimer, so I carry a lot of personal stuff as well as my tools in the basement, however with 11R22.5 tires most 2000 Marquis coaches were overloaded, as the owners discover when they weigh their coach.
Gerald