Pat, have used Innovative OTR Dyna beads with Tire Minder TPMS system installed with Michelin 12R 22.5 tires. I have ran this combo now for 30,000 miles with no problems. When checking air pressure I try to have valve stem at 12 o'clock position and then put a shot of air into valve stem to clear any beads that may possibly get under valve seat and let air leak out. Then check air pressure. If air does leak out while checking air pressure, keep adding air until valve seals. One nice thing about a TPMS is that you can check your pressures without putting a gauge on valve stems. I have found that checking pressures once or twice a year with a gauge is all that is needed if you monitor your TPMS diligently. Hope this helps.