I wouldn't mess with it unless you have been getting water in your primary fuel filter.
If you do decide to drain, wait until the tank is near empty and have some large containers ready. The plan would be too loosen the plug enough so any water would start dripping out, but not to remove the plug entirely. However when you loosen the plug enough for water to drip out, your about a half thread from the plug coming out completely. The containers are just in case the plug did come out all the way. Ask me how I know about this...
If you are finding water in the tank (in your filters) on more than one occasion, one of those drain fittings where you just open/close a petcock rather than removing the entire plug would be desirable as long as the bottom of the tank is high enough so there is no chance that drain valve could ever be knocked off. IMO.