Technically you can. What you give up is Amp Hour capacity and battery life (plates are much heavier in 6V golf cart batteries). If you have a bad 6V battery that is dragging the bank down, you could also run on a bank of 4, until you can get to a location that has one for replacement. If you rarely use the battery capacity of the bank and always stay plugged in at night, it might not be all that much of an issue. Sometimes boon docking cannot be helped in a pinch.
Later Ed