Michael,
I'll let the C12 owners opine on best RPM. When I drive in CA with the 55 MPH speed limit, I find it difficult to maintain 6th gear at less than about 63. To get from 5th to 6th I need to run up to about 63-64MPH and then back off to 60 MPH. Then I notice it will drop to 5th very easily; slight incline, wind gust, etc. Wondering if your tranny temps in 6th are partly caused by multiple shifts between 5 and 6. (This is with a C9 and Allison 3000 but seem to remember same issue with my C12 on a trip up I5). Also, the lower RPM results in the water pump running slower which also could contribute to what you are seeing.
Steve